Injection Instructions
Your complete step-by-step guide to safe, comfortable subcutaneous injections.
Prepare carefully, every time
Inspect the area to ensure the skin is clean and free of irritation, redness, or soreness. Wipe the chosen site thoroughly with an alcohol swab and allow it to dry completely before injecting. Alternate your injection site with each dose by switching between different sides of your abdomen.
Prepare the syringe with medication. Before withdrawing medication, double-check you're using the correct medication, at the correct dose. Remove the cap from the vial and clean the tip of the vial with an alcohol wipe. Pull back the plunger to fill the syringe with air up to your required dose. This balances the pressure inside the sealed vial, making it easier to draw the medication into the syringe.
Remove the cap from the needle and insert air into the vial. Carefully push the needle straight through the center of the rubber stopper, taking care not to bend it. Inject all the air into the vial. Be careful not to touch the needle so it stays sterile. To withdraw the medication, turn the vial and syringe upside down so the needle points upward, then pull back on the plunger to the prescribed dose.
Choosing the optimal injection site
The efficacy of injections depends on the careful selection of the injection site. Preferred locations for subcutaneous injections include the stomach, thigh, or upper arm—each providing an ideal fat layer to facilitate optimal medication absorption.
Stomach
A preferred site due to its accessibility and large surface area. The subcutaneous fat layer allows for smooth, reliable absorption. Choose an injection spot at least two inches away from your belly button.
Thigh
Another common site with an ideal fat layer for subcutaneous injections. Choose a spot on the front outer area of your thigh, making sure to avoid the inner thigh.
Upper arm
The back of the upper arm is a great alternative if you prefer a less visible injection site. Select a spot on the outer back portion of the arm, halfway between the shoulder and the elbow.
Proper injection technique
- 1
Prepare the injection - gather everything you need, wash your hands thoroughly, and check your medication. The liquid should be completely clear and colorless—do not use it if it appears cloudy, discolored, or contains visible particles.
- 2
Select an injection site on your abdomen, thigh, or upper arm.
- 3
Clean the injection site: wipe the chosen area with an alcohol swab and allow the skin to dry.
- 4
Inject the medication: Hold the syringe at a 90-degree angle, insert the needle swiftly and steadily into the skin, push the plunger to inject the medication, and hold it in place for 5 seconds before removing the needle.
- 5
Safely dispose of your supplies: Place used needles into a puncture-resistant, hard-shell container with a tight lid immediately after use. Store the container safely out of reach of children and pets.
How often should you rotate injection sites?
Rotate your injection sites: Follow your healthcare provider’s specific instructions or the medication guide for site rotation. As a general rule, use a different injection site each time to give your skin time to heal.
For example, with weekly injections, you can rotate between your abdomen, thigh, and upper arm. Switching sites prevents skin irritation, discomfort or changes in the skin at the injection site. Be sure to track your injection sites so you can easily switch areas every time.
Listen to your doctor
Safe and effective use of injectable weight-loss medication requires proper technique and alternating your injection sites. Always follow your healthcare provider’s specific instructions, and don’t hesitate to contact your care team if you have any questions or concerns.
Weight-loss medications are most effective when paired with balanced nutrition and lifestyle programs. These are designed to provide the ongoing support needed to develop healthy habits that last.